Author, year (Ref.)
Research type
Object*
Sample size
Factors
Gene
CpG sites
Method
Main result** (P value)
Gu, T. 2016[22] case control study H 954 smoking CYP11B2 4 sites bisulfite pyrosequencing in appendix
Peng, P. 2014[26]
case control study
H
97
smoking
ABCG1
/***
MSP
non-significant (0.132)
Jiang, W. 2021[25]
cohort study
H&M
7
smoking
CYP1A2
cg11473616
850K array
hypomethylation (<0.01)
Jin, Y. 2010[23] case control study H 40 smoking CYP1A1 / methyquant hypermethylation
Al Koudsi, N. 2010[24] cohort study H 161 smoking CYP2A6 / BSP followed by cloning PCR products on plasmids non-significant
Shang, Y. 2013[28] controlled experiment M 589 dust mite SLC8A3 / BSP followed by cloning PCR products on plasmids hypermethylation
Liang, Y. 2021[61]
cohort study
H
248
PM2.5
CYP1B1
/
MethylTarget
hypomethylation (<0.05)
Amenya, H. Z. 2016[29]
controlled experiment
M
282
Dioxins
CYP1A1
2 sites
MSRE-qPCR✟*
hypomethylation (<0.05)
Li, H. 2014[62]
control study
M
100
N-hexane
CYP11A1 CYP17A1 CYP1A1
/
MeDiP
hypermethylation
Jiménez-Garza, O. 2020[63]
controlled experiment
H
124
toluene exposed
CYP2E1
/
bisulfite pyrosequencing
hypomethylation (<0.05)
Jiménez-Garza, O. 2015[64]
cohort study
H
190
benzene exposure
CYP2E1 GSTP1
10 sites
bisulfite pyrosequencing
in appendix