Key points:
- Diagnosis of AIFRS should be alert in the immunocompromised patient
presenting with new-onset, rapidly progressive sinusitis with
facial-cranio-orbital spread.
- Extended debridement should be considered on a case-by-case basis.
- Antifungal agent contributed greatly to the outcome of AIFRS.
- Prognosis mostly up to the balance of underlying disease and fungal
invasion, more emphasizes should be focused on comprehensive
treatment.
- AIFRS with facial-cranio-orbital involved often had a disastrous end.