Conclusion
Misoprostol is an inexpensive and effective method of termination of
pregnancy and is a good alternative in countries where mifepristone is
not available.2 Considering all the data in the
literature to date, achieving effective results with the LD misoprostol
regimen compared to previously reported doses in pregnancies with or
without a history of cesarean section below 34 weeks of gestation may
lead to a review of algorithms even presented by
FIGO.3, 5 The ’low-dose vaginal misoprostol’ regimen
is an effective method with low maternal morbidity and high success
without increasing the total treatment time. Especially in patients with
a history of cesarean section where the ’experience of ToP with
misoprostol’ have relatively high risk , and in all ToP’s below 34
weeks, achieving a high birth rate without increasing the uterine
rupture rate suggests that it is a safe approach.
Disclosure of interests: The authors report no conflict of
interest.
Contribution to authorship: All authors conceptualised and
designed the study. TSS designed the study, wrote the first draft of the
paper, interpreted the data. OD analysed and interpreted the data, and
wrote the article. SBT, OT, HC, SBI and EY were involved in the sample
collection. IHK and RH revised and contributed to the intellectual
content of the manuscript. All the authors approved the final article.
Details of ethics approval: The study was conducted according
to the guidelines of the Declaration of Helsinki and approved by the
local Institutional Review Board (IRB) (approval number: 1105085).