Conclusion
Misoprostol is an inexpensive and effective method of termination of pregnancy and is a good alternative in countries where mifepristone is not available.2 Considering all the data in the literature to date, achieving effective results with the LD misoprostol regimen compared to previously reported doses in pregnancies with or without a history of cesarean section below 34 weeks of gestation may lead to a review of algorithms even presented by FIGO.3, 5 The ’low-dose vaginal misoprostol’ regimen is an effective method with low maternal morbidity and high success without increasing the total treatment time. Especially in patients with a history of cesarean section where the ’experience of ToP with misoprostol’ have relatively high risk , and in all ToP’s below 34 weeks, achieving a high birth rate without increasing the uterine rupture rate suggests that it is a safe approach.
Disclosure of interests: The authors report no conflict of interest.
Contribution to authorship: All authors conceptualised and designed the study. TSS designed the study, wrote the first draft of the paper, interpreted the data. OD analysed and interpreted the data, and wrote the article. SBT, OT, HC, SBI and EY were involved in the sample collection. IHK and RH revised and contributed to the intellectual content of the manuscript. All the authors approved the final article.
Details of ethics approval: The study was conducted according to the guidelines of the Declaration of Helsinki and approved by the local Institutional Review Board (IRB) (approval number: 1105085).