Fig. 1
a) Clinical findings. Numerous papules and nodules on the trunk and extremities are evident. b) Histopathological findings of the skin (hematoxylin-eosin stain, × 20). Amorphous eosinophilic nodular lesions can be noted in the dermis and subcutis. c ) Histopathological findings of the skin (hematoxylin-eosin stain, ×100). Amorphous eosinophilic nodular lesions are present around vessels.d ) Histopathological findings of the skin (direct fast scarlet stain, ×100). An amorphous substance around vessels is stained with orange dye. e ) Histopathological findings of the skin (×100). Apple-green-birefringence with polarization is evident in the amorphous substance around vessels. f) Histopathological examination of the bone marrow (hematoxylin-eosin stain, ×400). Proliferation of lymphocytes and plasmacytes without atypia is evident. g)Histopathological examination of the bone marrow (hematoxylin-eosin stain, ×1000). Lymphoplasma cells with Dutcher’s bodies without atypia are evident. Dutcher’s bodies are indicated by arrowheads. h ) Histopathological examination of the bone marrow (×400). Some lymphocytes react with anti-CD20 antibody (Nichirei Biosciences, Tokyo, Japan).