Fig. 1
a) Clinical findings. Numerous papules and nodules on the trunk
and extremities are evident. b) Histopathological findings of
the skin (hematoxylin-eosin stain, × 20). Amorphous eosinophilic nodular
lesions can be noted in the dermis and subcutis. c )
Histopathological findings of the skin (hematoxylin-eosin stain, ×100).
Amorphous eosinophilic nodular lesions are present around vessels.d ) Histopathological findings of the skin (direct fast scarlet
stain, ×100). An amorphous substance around vessels is stained with
orange dye. e ) Histopathological findings of the skin (×100).
Apple-green-birefringence with polarization is evident in the amorphous
substance around vessels. f) Histopathological examination of
the bone marrow (hematoxylin-eosin stain, ×400). Proliferation of
lymphocytes and plasmacytes without atypia is evident. g)Histopathological examination of the bone marrow (hematoxylin-eosin
stain, ×1000). Lymphoplasma cells with Dutcher’s bodies without atypia
are evident. Dutcher’s bodies are indicated by arrowheads. h )
Histopathological examination of the bone marrow (×400). Some
lymphocytes react with anti-CD20 antibody (Nichirei Biosciences, Tokyo,
Japan).