3.3 β-endorphin is a biomarker of itch in arsenic-exposed
participants
The characteristics of the participants are shown in supplementary Table
S3. Among the 8 mediators of itch, we identified serum β-endorphin as a
significant biomarker that was does-dependently associated with the
intensity of itch in arsenic-exposed participants in Shimen (Figure 3).
In contrast, the levels of substance P, nerve growth factor, histamine,
interleukin-31, IgE, endothelin-1, and 5-hydroxytryptamine were not
statistically different among the three groups.