Declaration of Competing Interest:
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Author contributions: All authors participated in the field survey and collection of biological samples. X.H., Y.X., and D.J. performed the dermatological examinations. Senior dermatologists J.S., M.C., and X.C. were responsible for quality control for diagnosis. X.H., M.H., and Z.H. measured the biological samples. Y.H. performed the animal experiment. X.H., M.S., and S.Y. analyzed the data and drafted the manuscript. Z.H., M.H., J.S., M.C., X.C., and M.S. designed the study, critically reviewed and revised the manuscript. X.C. and M.S. obtained the funding and contributed the conceptualization of the study. All authors gave final approval to the version submitted for publication.