Secondary efficacy outcomes
After 6-month EPIT, all but one dog, who maintained the low initial score (8 in 0-45 score range), improved their QoL scores, establishing a QoL success rate of 93.3% (14/15), with a 58.4% mean improvement. If a > 50% QoL improvement is considered, 66.7% of dogs (10/15) reached this target at six months. Moreover, mean QoL scores significantly improved over six months (p=0.000014), being already evident at three months (p=0.000033) (table 3, figure 3). Notably, 13/15 dogs (86.7%) had improved QoL scores at 3-month EPIT (54.6% mean improvement).
Regarding allergen-specific IgE serology, 46.7% of dogs (7/15) were desensitised to at least one mite over six months, whereas 6/15 dogs (40%) had achieved it at three months. Noteworthy, 2/15 dogs (13.3%) fully desensitised to all mites at both 3-month and 6-month evaluations.