Drawbacks (-) | Drawbacks (-) | Drawbacks (-) | Benefits (+) |
Indications
|
high-grade atrioventricular block
|
cardiac resynchronization therapy
|
meta-analysis results: pre-implantation LVEF <40% females age >80 years |
Randomized studies | Protect-Pace study | SEPTAL CRT study | |
Patients | 240 | 263 | |
Results | Decrease in LVEF, no difference in HF hospitalizations, AF, BNP, and mortality | No difference in reduction of LVESV and composite clinical endpoint of deaths and HF hospitalizations |