Objective
The primary aim was to systematically review the effectiveness and
safety of pharmacological or non-pharmacological interventions used to
prevent or treat platinum-induced ototoxicity in adult cancer patients.
Even though ototoxicity is a less common adverse effect of other
chemotherapy agents, we consider that studies could report ototoxicity
interventions for multiple chemotherapy regimens. So our secondary aim
was to assess pharmacological or non-pharmacological interventions for
ototoxicity caused by other chemotherapy agents in adult cancer
patients.