SALL4 as an indicator for the diagnosis of Hepatoid Carcinoma of the Ovary: A case report and literature review

Jiana Li^1,2, Xiaohua Wu^1,2*

¹ Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, PR China

² Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, PR China

* Correspondence: Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, PR Chinawu.xh@fudan.edu.cn (X. Wu)

Abstract

We report a case of a postmenopausal woman presenting with lower abdominal pain and vaginal bleeding. She went through a maximal debulking surgery and the pathological biopsy revealed hepatoid carcinoma of the ovary (HCO). Immunohistochemical assay demonstrates SALL4 as an indicator to differentiate HCO from Hepatocellular carcinoma (HCC).