01/04/2015 Initial presentation with lower abdominal pain and vaginal bleeding
02/04/2015 Abdominal CT and MRI revealed bilateral annexal masses and pelvic effusion
03/04/2015 Laboratory tests showed AFP 3630ng/ml, CA125 337.9 U/ml, HE4 142.7pmol/L
20/04/2015 Maximal debulking surgery
29/04/2015 Discharge from hospital
11/05/2015 Administration of the first course of chemotherapy (paclitaxel and carboplatin)
11/05/2016 Administration of the ninth course of chemotherapy (paclitaxel and carboplatin)
19/08/2016 MRI showed no sign of recurrence, with serum AFP and CA125 in normal range
01/12/2016 MRI showed no sign of recurrence, with serum AFP and CA125 in normal range
31/03/2017 PET/CT showed no abnormal increase in FDG metabolism through systemic imaging
April to May/2017 Laboratory tests showed rapidly elevated serum CA125 and AFP
07/05/2017 Complaint of abdominal pain, distension and stop defecating
08/05/2017 MRI revealed pelvic effusion and metastasis in omentum, peritoneum and mesenteric nodules
19/05/2017 Start chemotherapy (paclitaxel and carboplatin)
12/10/2017 Stop chemotherapy due to severe adverse events
20/11/2017 CT revealed pleural effusion and a large amount of peritoneal effusion with multiple small nodules in the peritoneum and swollen retroperitoneal lymph nodes
In Early 2018 Our patient passed away due to cachexia and multiple organ failure