Introduction
Dravet syndrome, also called severe myoclonic epilepsy in infancy. This
disorder usually manifests in the first year as febrile or afebrile
clonic and tonic–clonic, generalized, and unilateral seizures, often
prolonged, in an apparently normal infant. Later, multiple seizure
types, mainly myoclonic, atypical absences, and focal seizures appear,
as well as a slowing of developmental and cognitive skills, and the
appearance of behavioral disorders. Up to 80% of patients are tested
positive for SCNA1 mutation.1 Dravet syndrome
is usually accompanied by many comorbidities including psychiatric
issues, urinary tract and bowel issues, sleep disorders and
others.2 Here, we describe an adolescent with Dravet
syndrome who was diagnosed with B-cell type acute lymphoblastic leukemia
(ALL) and suggest a possible correlation between these two disorders.