PROPERTIES OF SALT CLA+ T CELL FEATURES
Only a subset of T cells displays skin affinity. Selective skin homing.
Skin-related lymphocytes produce immunoregulatory molecules. Memory phenotype with broad capacity for cytokine production.
Immune recognition of antigen in the skin. Preferentially respond to antigens related to skin.
HUMAN SKIN DISEASES BESIDES AD CLA+ T CELL INVOLVEMENT
Allergic contact dermatitis Response to nickel, cobalt, and chromium metal allergy.100
Alopecia areata Th2/Tc2 activation.101
Drug-induced allergic reactions Response to drugs.102
Guttate psoriasis Streptococcus pyogenes induces Th17 response.103
Herpes Simplex CD8+ T anti-viral response.104
Leprosy Antigen-specific response.105
Melanoma Skin metastasis and response to therapy.106
Papuloerythroderma Higher proportion than CLA- of IL-4, IL-13, IL-22 and IL-31 production.107
Plaque Psoriasis Response to Streptococcus pyogenes and relation with clinical status.108
Rosacea Response to demodex.109
Skin dengue infection Response to Dengue.110
Vitiligo Response to autoantigens.111