Acknowledgements: Writing and editing assistance, including
preparation of a draft manuscript under the direction and guidance of
the authors, incorporating author feedback, and manuscript submission,
was provided by James A. Shiffer, RPh and Jamie Dermatis, DPM (Write On
Time Medical Communications, LLC, NJ).
Conflicts of interest: SCB, AS, LEK, and AA are employees of
Stealth BioTherapeutics (Newton, MA).
Funding : The trial was funded by Stealth BioTherapeutics
(Newton, MA).
Data availability: The data that support the findings of this
study are available from the corresponding author upon reasonable
request. Some data may not be made available because of privacy or
ethical restrictions.
Clinical trial registration: This Phase 1 study was not
preregistered following guidelines in 42 Code of Federal Regulations
(CFR) Part 11.