Maternal outcomes
Maternal outcomes are described in Table 2 and Table 3. Analyses were adjusted for maternal age, progestational BMI, ART pregnancy, operative hysteroscopy, prior cervical surgery, prior sPTB, GA at diagnosis, amniotic membrane prolapse, WBC, CRP at diagnosis. Compared with the control group, median GA at delivery was significantly higher (30.5 vs 27 weeks, Bate: 3.40, 95% CI:2.13-4.67, p<0.001) and median pregnancy latency was significantly longer (56 vs 28 days, Bate:24.04, 95% CI:13.31-34.78, p<0.001) in the case group. McDonald-Shirodkar combined technique was associated with significantly lower incidence of sPTB at <28 weeks (16.7% vs 57.1%, aOR: 0.15, 95% CI: 0.05-0.44, p= 0.001), <30 weeks (38.1% vs 76.8%, aOR: 0.17, 95% CI: 0.06-0.48, p= 0.001), <32 weeks (54.8% vs 88.1%, aOR: 0.16, 95% CI: 0.05-0.50, p= 0.002), and <34 weeks (73.8% vs 92.9%, aOR: 0.22, 95% CI: 0.05-0.90, p= 0.036). The mode of delivery and the rates of PPROM <34 weeks did not differ between the two groups. The Kaplan–Meier curves in Figure 2 showed that the cumulative percentage of patients with delayed birth was significantly higher in case group than in the control group. The log-rank test showed a significant increase in pregnancy prolongation (p < 0.001).