Figure 2 : CNS Emryonal tumor. IHC. Synaptphysin. Tumor celles express neuronal marquer. HEx20
Our patient underwent a thoracic, abdominal, and pelvic CT scan that showed pulmonary embolism with no secondary localizations of the tumor, a cerebral residual tumor of 4 cm, and a bone scan that was normal.
Seeing the recurrence of the patient’s symptoms after two months, an MRI was performed that showed tumor recurrence with edema and hemorrhagic areas and meningeal carcinomatosis. Another surgery was performed with total resection, with cerebrospinal fluid analysis revealing no malignant cells. A second recurrence of intracranial hypertension symptoms led to the discovery of areas of meningeal enhancement involving the supratentorial region of the brain.
The patient began to receive two of the planned eight cycles of platinum- and alkylator-based chemotherapy. This initially consisted of cisplatin, vincristine, and cyclophosphamide (VIP), with improvement in the patient’s presenting symptoms.