Acknowledgments:
Study design by MOB, SJJ, CBB, HJMcS and JS. Experiments performed by MOB with PJ, KB for flow cytometry and with HM for Methocult assays. MOB, CCB and HJMcS analysed and discussed the data. MOB and JS drafted the manuscript and MOB, HM, SJJ, CCB, HJMcS and JS critically reviewed and revised the manuscript. JS obtained the funding. MM developed and provided the MC-21 antibody. All authors gave final approval to the version submitted for publication.
Flow cytometry data was generated with support from the QMRI Flow Cytometry and cell sorting facility, University of Edinburgh. This work was funded by UKRI-MRC grant MR/T029668/1. This UK funded award is part of the EDCTP2 programme supported by the European Union. CCB is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (grant number 206234/Z/17/Z). We thank Amy Buck (University of Edinburgh, United Kingdom) for providing H. polygyrus L3 larvae and Samanta Mariani (University of Edinburgh, United Kingdom) for advice on bone marrow Methocult assays.