Ethical clearance and fulfillments of other regulatory affairs
This is to state that the present study was carried out in accordance
with the National Institutes of Health, USA guidelines and the
institutional ethical concerns, relevant guidelines and regulations were
maintained throughout the investigation. This study confirms that all
experimental protocols were approved by the institutional (Oriental
Institute of Science and Technology) Ethics Committee
(oist/EC/hu/bt/16/). This is also to state that informed consent was
obtained from all participants who were at their post-menopausal age.
Female Wistar rats were purchased from a small-animal firm house (Govt.
registered) that follows all ethical norms and maintain requisite
regulatory affairs. The firm house is a Government accredited
(CPCSEA-Committee for the Purpose of Control and Supervision of
Experiments on Animals: Reg. no 1A2A/PO/BT/S/15/CPCSEA. organization
under the Dept of Animal Husbandry and Dairy, Ministry of Agriculture
and Farmer’s Welfare, Govt. of India. Proper permissions for all animal
experiments, were obtained from the Institutional (Oriental Institute of
Science and Technology) Review Board.