Fig. 5. KVX-053 treatment decreases the phosphorylation of I-kappa B alpha (IκBα) and STAT3 and activation of NLRP3 inflammasome.Bands were normalized to β-actin and are shown as fold of control. Means ± SEM; n = 7-8 mice/group; *P < 0.05; ***P < 0.001 with one-way ANOVA and Tukey’s test.