7.1. Glucocorticoid-induced leucine zipper (GILZ)
Glucocorticoid-induced leucine zipper (GILZ) is a crucial component of the anti-inflammatory response. It is a protein consisting of 137 amino acids and is rapidly induced by the administration of glucocorticoids in various cell types. GILZ serves dual functions as a transcription factor, activating different genes, and as a cytoplasmic protein, interfering with various signaling pathways (Ronchetti et al., 2015; Bruscoli et al., 2021; Bereshchenko et al., 2019).