3.1 - Maresins
Maresins are lipid metabolites derived from DHA (docosahexaenoic acid) and are produced by macrophages and neutrophils. They possess potent anti-inflammatory and pro-resolving properties (Serhan et al., 2009). Furthermore, recent research has revealed the existence of different conjugates of maresins that are generated through enzymatic hydrolysis in the tissue. These conjugates are known as maresin conjugates in tissue regeneration (MCTRs) (Levy et al., 2020).