7.1. Glucocorticoid-induced leucine zipper (GILZ)
Glucocorticoid-induced leucine zipper (GILZ) is a crucial component of
the anti-inflammatory response. It is a protein consisting of 137 amino
acids and is rapidly induced by the administration of glucocorticoids in
various cell types. GILZ serves dual functions as a transcription
factor, activating different genes, and as a cytoplasmic protein,
interfering with various signaling pathways (Ronchetti et al., 2015;
Bruscoli et al., 2021; Bereshchenko et al., 2019).