Figure 1 The locations for study area(A), home addresses of subjects (B,
D), outpatient clinics and monitoring stations (C, D), and the incidence
of eczema in five different districts(B).
6640 mothers of newborns without congenital disease participated in the
survey, of whom 139 were multiples, and after further exclusion, a total
of 6501 singleton births without congenital disease served as the
baseline population for the birth cohort, and after 2 years of
follow-up, a total of 5819 study subjects completed follow-up, with a
10.5% (682/6501) lost to follow-up rate over 2 years. A total of
1155(19.8%) of the 5819 study subjects had eczema before the age of 2
years, with 996(17.1%) children with eczema at 1 year of age and 229
(3.9%) with eczema at 2 years of age (Figure 2). A higher proportion of
children with eczema had a history of parental atopy (22.08% vs
18.83%), maternal working during pregnancy (65.71% vs 60.06%), high
monthly household income (89.52% vs 86.60%), maternal primipara
(53.77% vs 47.81%), infrequent window opening (51.95% vs 60.50%),
and use of air purifiers (23.64% vs 20.44%) compared with non-eczema
study subjects(P <0.05) (Table1).