3.1 Clinical characteristics of women with ICP and normal pregnant women
Table 1 depicts the clinical characteristics of ICP and normal pregnant women. There was no significant difference in maternal age, body mass index (BMI), gravity number, parity number and placenta weight between ICP and normal pregnant group (p >0.05), the gestational age at delivery was lower in both mild ICP and severe ICP group. The levels of TBA, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) were significantly higher in both mild and severe ICP group compared with normal pregnancy. In addition, ICP patients had significantly lower fetal birth weight compared with healthy controls.