Figure 1
Angiotensin II infusion promotes immune cell infiltration in the brain. A: Angiotensin II-induced hypertension (n=6-8). All data are mean ± S.E.M. *P<0.05. Two-way ANOVA with Tukey’s test.B: Representative flow cytometry dot plots showing gating strategy for microglia (CD45+ low) and total leukocytes (CD45+ high) from the brains of mice infused with vehicle or angiotensin II. The effect of angiotensin II infusion on C:CD45+low microglia, D: CD45+ leukocytes,E: CD3+ T cells, F: CD4+ T cells, G: CD11b+ myeloid cells, H: Ly6G+ neutrophils, I:Ly6C+low monocytes, J:Ly6C+high monocytes, K: F4/80+ macrophages and L: CD19+ B cells in the brain (n=6-8). All data are mean ± S.E.M. *P<0.05. Student’s unpaired t-test.