Statistical analysis
Results are expressed as mean ± S.E.M. Power calculations were performed using G*Power. Statistical analyses between groups were performed using Student’s unpaired t-test, one-sample t-test, or a one- or two-way ANOVA followed by a Tukey’s or Sidak’s post-hoc test, as appropriate. P<0.05 was considered to be significant. RNA sequencing data were analysed using R Studio. GraphPad Prism software (version 8.0, GraphPad Software Inc., USA) was used to perform all other statistical analyses.