Results
Despite reduced respiratory virus circulation, HRV type A and C infections persisted in children, with sporadic detection of HRV B and other respiratory viruses. A resurgence of HRV A cases in November 2020, dominated by genotypes A47 and A101, was observed during the relaxation of PHSMs between the third and fourth waves of COVID-19. Strict PHSMs implemented during the fourth wave, including school closures, substantially reduced respiratory virus circulation, though overall diversity increased due to heightened vigilance. HRV genotype A49 became predominant in May 2021 upon relaxation of control measures, with phylogenetic analysis suggesting persistence of multiple transmission lineages despite strict PHSMs. Genotypes A49 and A47 were frequently associated with upper respiratory tract infections, highlighting their epidemic potential.