Lead Authors
|
Dr James Sweatman (Royal Free London NHS Foundation Trust)
Ms Sarraa Al-Mahdi (London North West University Healthcare NHS
Trust)
|
Second Authors |
Dr Dagan O Lonsdale (St. George’s University London,
St. George’s University Hospitals NHS Foundation Trust) |
Third Authors
|
Dr Susannah Leaver (St. George’s University Hospitals NHS Foundation
Trust)
Professor Andrew Rhodes (St. George’s University Hospitals NHS
Foundation Trust)
|
Corresponding Author
|
Dr Dagan O Lonsdale
dlonsdal@sgul.ac.uk
|
Author Contribution
Statement
|
J.S. and S.A-M. developed the protocol for the presented research. J.S.,
S.A-M. and D.L. participated in data collection and analysis. D.L.
performed the simulated modelling. S.L. and A.R. verified the analytical
methods. All authors discussed the results and contributed to the final
manuscript.
|
Keywords |
Levetiracetam, Keppra, continuous renal replacement therapy,
renal replacement therapy, haemodialysis, haemofiltration,
pharmacokinetics, PKPD, PK. |
Word Count
|
ABSTRACT 240 words
MAIN TEXT 3,212 words
|
Table Count |
4 |
Figure Count |
5 |
Ethics & Integrity
Statement
|
Funding was received from the St. George’s Hospital Charity and had no
impact on the authors’ independence or execution of the research. The
authors declare no conflicts of interest in this work. No ethics or
patient consent approval were required for this review article. Our
protocol was registered on PROSPERO (CRD42022300754) prior to the
commencement of the research. No materials within this paper were
reproduced from other works. All figures and diagrams are original to
this paper.
|
Data Availability
Statement
|
The data that support the findings of this study are available from the
corresponding author upon reasonable request.
|