Figure 4 Serum-free culture of CHO/GEV_scFv-Fc cells with the
addition of 4-OHT. Growth response (A) and viability(B) during culture. Symbols: gray squares, no addition; closed
squares, 0.01 µM; closed triangles, 0.05 µM; open circles, 0.1 µM;
closed diamonds, 0.5 µM; closed circles, 1 µM. scFv-Fc concentration(C) and specific production rate (D) during culture.
The distinction of columns is the same as described for Figure 2.