Figure 3. Histopathological findings of vesicles
a) Hematoxylin-eosin stain, × 400. Intraepidermal blisters with large multinucleated giant cells and intranuclear inclusion bodies shown as a pale amorphous substance are evident. b) Direct immunofluorescence, × 1,000. The nuclei of cells in vesicles are reactive to an anti-VZV antibody (Denka, Tokyo, Japan), as indicated by white arrowheads.