Conclusion
In this study we conducted a nationwide analysis of blood serum
metabolites of patients admitted to hospital due to CCHF. We employed
NMR spectroscopy as a novel approach to characterize host viral response
and pathogenesis of CCHFV. Among detected compounds, most prevalent of
them were detected to be SAH and carnosine and notable increases in
compounds relating to TCA cycle, nucleic acid synthesis and redox
related coenzymes in the cell.