Conclusion
Our case report involves the conversion of a metastatic non-functional NET into a functional malignant insulinoma. The key clinical points from this case report are as follows: 1) When a non-functional neuroendocrine tumor converts into a functional one, the prognosis worsens significantly. 2) Alternative treatments beyond conventional chemotherapy are required for patients with aggressive insulinomas. 3) More research is required to evaluate treatments such as Everolimus and Sunitinib for their use in cases of malignant insulinomas.