Subgroup analysis
Figure 4 presents the prevalence of infertility for participants or
studies with different characteristics. In terms of geographical region,
the prevalence of infertility for participants from Africa, Asia,
Europe, North America, and Oceania were 16.73%, 14.91%, 13.83%,
8.84%, and 16.45% respectively (P <0.001). There are
differences between each other. The prevalence rates in survey years
groups were 9.06, 10.81, 14.32, and 17.2 respectively (P<0.001). The prevalence of infertility increases with the
number of years, Showing a significant linear trend
(Ptrend <0.001). Combined rates of
infertility Compared to cross-sectional studies, the prevalence is
significantly lower in cohort or prospective follow-up studies (9.75%
vs 12.93%, P <0.001). Globally, the prevalence of
infertility for women ≥35 years old is significantly higher than that
for women <35 years old (11.68% vs 5.92%,Ptrend <0.001). From low to high levels
of literature bias, the prevalence increased from 9.72% to 11.75 to
16.7% (Ptrend <0.001). Detailed
subgroup analysis forest maps were shown in Figure S3 to S6. The funnel
plot results are shown in Figure S7.