5. CONCLUSION
Overall, relying on the robustness of our study, we were able to confirm
that the use of IU and non-IU manipulators during TLH results in
comparable oncological outcome in early-stage, low-grade EEC. Future
work should specifically focus on investigating the role of manipulators
in other subsets of endometrial cancer patients in terms of tumour
stage, grade, and histotype. In patients with high-risk endometrial
cancer, implementation of solely those manipulators that do not
compromise oncological prognosis will not only facilitate gynaecologists
in their choice of manipulator, but also further improve patient care.
Additionally, potential advantages of IU manipulators should be
explored, including their impact on surgery time, complication rate, and
learning curve.