5. CONCLUSION
Overall, relying on the robustness of our study, we were able to confirm that the use of IU and non-IU manipulators during TLH results in comparable oncological outcome in early-stage, low-grade EEC. Future work should specifically focus on investigating the role of manipulators in other subsets of endometrial cancer patients in terms of tumour stage, grade, and histotype. In patients with high-risk endometrial cancer, implementation of solely those manipulators that do not compromise oncological prognosis will not only facilitate gynaecologists in their choice of manipulator, but also further improve patient care. Additionally, potential advantages of IU manipulators should be explored, including their impact on surgery time, complication rate, and learning curve.