Fig. 4 Postoperative refractive outcomes
a: Uncorrected distance visual acuity. b : Uncorrected distance visual acuity versus corrected distance visual acuity. c : Spherical equivalent refraction accuracy. d : Postoperative refractive cylinder (n=30 eyes in each group).
CDVA = corrected distance visual acuity; FPR = first Purkinje reflex; PC = pupil center; UDVA = uncorrected distance visual acuity.
For the Evaluation of Posterior Capsular Opacification (EPCO) analysis, based on picture quality, there were 60 eyes (of 30 patients) available at 3-years of follow up. The mean PCO score of the EPCO analysis was 0.338±0.243 (range: 0.000 to 0.690) for the PC group and 0.347±0.230 (range: 0.000 to 0.720) for the FPR group, reflecting no statistical difference between them (mean diff.: -0.009±0.142, 95%: -0.060 to -0.041; p=0.725). Seven eyes (23.3%) of the PC group and 6 eyes (20%) of the FPR group did not display any signs of PCO, whereas 23 of the PC eyes (76.7%) and 24 of the FPR eyes (80%) displayed an EPCO score from > 0 to 1 (none to minimal).
Regarding aberrometry data, a statistically significant difference was found between groups for internal high-order (HOAs) aberrations (mean diff.: 0.016±0.023 µm, 95% CI: 0.008 to 0.024; p<0.01) and for total internal root-mean-square (RMS) aberrations (mean diff.: 0.007±0.008 µm, 95% CI: 0.004 to 0.009; p<0.01), with higher values in the PC group; comparison of low-order aberrations (LOAs) between groups showed no statistically significant difference (mean diff.: 0.004±0.010 µm, 95% CI: 0.000 to 0.007; p= 0.073).
A positive significant but weak correlation (p value<0.05; R2<0.05) was found between distance from the IOL center to the visual axis (IOLC-FPR) and internal (HOAs and LOAs) RMS in the total eye population (p<0.001; R2=0.38) (Figure 5).