Figure 3. Associations of RSV and RV-specific IgG levels with
personal determinants and seasons of blood sampling in children (EGEA1,
n=531) and adults (EGEA2, n=1241)
Multivariable mixed linear regression models were used to estimate beta
and corresponding 95% CIs for virus-specific (RSV/RV) antibody levels
associated with personal determinants and the seasons of blood sampling.
Error bars represent 95% CIs.
EGEA: Epidemiological study on the Genetics and Environment of Asthma;
RSV: respiratory syncytial virus; RV: rhinovirus; BMI: body mass index;
Jan-Mar: January-March; Apr-Jun: April-June; Jul-Sep: July-September;
Oct-Dec: October-December.
Beta were estimated from linear mixed regression models for repeated
data (random effect on family) with IgG level as dependent variable and
age (continuous), sex, BMI (continuous), season of blood sampling (4
seasons), tobacco (passive in EGEA1, active in EGEA2), allergic
sensitization and ever-asthma as predictors.
*age and BMI were standardized (divided by their Standard deviation
(SD)), thus beta are reported for 1SD increased. Standard deviation (SD)
of age in EGEA1: 2.85 years; SD of age in EGEA2: 16.7 years; SD of BMI
in EGEA1: 2.91 kg/m2; SD of BMI in EGEA2: 4.25
kg/m2.