Table Captions
Table 1 . Arithmetic means (SD) of SBP, DPP, and HR measured during CPT, at day -1 and day 10, following administration of zamicastat and placebo (PP-PD population, n=21).
Table 2. Arithmetic means (SD) of the differences between cold stimulus and rest phases for SBP, DPP, and HR measured during CPT, at day -1 and day 10, following administration of zamicastat and placebo (PP-PD population, n=21).
Table 3. Comparison of zamicastat against placebo for cold stimulus and rest phases (at day 10 adjusted to baseline) (PP-PD population, n=21).
Table 4. Mixed effect model results of mean arterial pressure and hemodynamic parameters during cold pressor test – Least square means differences between zamicastat and placebo for the difference between cold stimulus and rest phases adjusted to baseline (PP-PD population, day -1, n=21).
Table 5. Mixed effect model results of plasma catecholamines concentration – differences between zamicastat and placebo – Least square means before and after CPT at day 10, adjusted to baseline (PP-PD population, n=21).