Stachys spinosa
The extract exhibited inhibitory effects against all oral bacteria andS. aureus , with MIC values ranging from 0.15 mg / ml (P.
micra ) to 2.50 mg / ml (S. oralis , E. faecalis , S.
aureus ). However, notable bactericidal effects were observed only for
obligate anaerobes (MBC of P. micra : 0.30 mg / ml), S.
oralis (5.00 mg / ml), and S. aureus (10.00 mg / ml, as shown in
Table 15.
No biofilm production was detected at an extract concentration of 10.00
mg / ml. However, concentrations as low as 2.50 mg / ml were sufficient
to inhibit biofilm formation, categorized as C2 (Figure 3).