Cistus monspeliensis
The ethyl acetate extract exhibited potent antimicrobial activity against oral pathogens, with MBC values ranging from 0.04 mg / ml (P. micra ) to 5.00 mg / ml for E. faecalis . It also demonstrated significant activity against C. albicans . However, except for the antimicrobial effect of DMSO (as shown in Table 3), the extract had no impact on E. coli . The most pronounced inhibitory effect was observed at 0.04 mg / ml on P. micra , closely followed by 0.08 mg / ml for S. oralis and P. gingivalis . The mean minimum inhibitory concentration (MIC) and MBC values for the typical skin microbe S. aureus were 0.60 mg / ml.
Figure 3 indicates that the biofilm formation of S. mutans was not influenced by the tested concentrations of the ethyl acetate extract.