Cistus creticus
The mean MIC and MBC values for the ethyl acetate extract against the tested bacterial and fungal strains are summarized in Table 2. The MIC values for the inhibited bacterial strains ranged from 0.04 mg / ml (P. gingivalis , P. micra ) to 5.00 mg / ml (S. sobrinus ). The MBC values indicated that 99.9% of the bacterial strains were killed at concentrations ranging from 0.04 mg / ml (P. micra ) to 5.00 mg / ml (S. aureus ). E. faecalis(MIC = 2.50 mg / ml) and S. sobrinus were inhibited but not completely eradicated in the test. S. mutans , E. coli , andC. albicans did not appear to be significantly affected by the extract.
Similar to the MIC/MBC assays, the biofilm plate assay showed no detectable effect on biofilm formation (C3) by S. mutans , as depicted in Figure 3.