Phlomis cretica
Table 8 presents the inhibitory effects of the ethyl acetate extract,
particularly on the bacterial strains. When considering the impact of
DMSO, the extract showed no significant effect on E. faecalis ,E. coli , and C. albicans . The minimum inhibitory
concentration (MIC) values ranged from 0.04 mg / ml (P. micra ) to
2.50 mg / ml (S. sobrinus , S. aureus ). The minimum
bactericidal concentration (MBC) values indicated the persistence ofS. mutans , S. sobrinus , C. albicans , E.
faecalis , and E. coli in the presence of the ethyl acetate
extract from P. cretica , while all other strains were killed at
concentrations ranging from 0.08 mg / m (P. micra ) to 2.50 mg /
ml (S. aureus ).
In the biofilm plate assay, no accumulated biofilm was observed in the
presence of 5.00 mg / ml of the ethyl acetate extract. With over five
dilution steps, including 0.15 mg / ml (as shown in Figure 2), a
moderate biofilm formation was observed, while lower concentrations fell
into category C3, indicating no detectable effect on biofilm formation.