2.4.1 Pharmacokinetic study of single dose
Forty-four subjects at 6 dose levels of 0.2-2.0 mg/kg participated in the pharmacokinetic assessment of a single dose. Serum was taken within 5 min before administration, 5min, 15min, 30min after the start of administration, 5 min, 20 min, 40 min, 1h, 1.5h, 2h, 3h, 4h, 6h, 8h, 12h, 24h after the end of the administration to test the blood drug concentration.