Study design and participants
This retrospective cohort study reports reproductive intentions and
outcomes of women who underwent fertility-sparing surgery or fertility
preservation procedures for invasive cervical cancer in a tertiary
referral clinic for gynecological oncology in the Netherlands. Using a
computerized database, patients ≤ 45 years old, diagnosed with invasive
cervical cancer stage IA2 to IVA and who desired to maintain
reproductive potential between January 2009 and January 2020 were
identified. Patient, tumor and treatment data were retrieved from
medical files. Data on reproductive intentions and pregnancy outcomes
were derived from both medical files and postal questionnaires sent to
all but deceased patients.