No. of events, n/total (%) Unadjusted model Unadjusted model P Model 1 P Model 2 P
Normal 124/801 (15.5) 1 (Reference) 1 (Reference) 1 (Reference) 1 (Reference)
AUC quartile (min–max)
Q1 (364.5–449.0) 12/64 (18.8) 1.26 (0.65–2.43) 1.26 (0.65–2.43) 0.490 1.14 (0.56–2.34) 0.720 1.00(0.43–2.29) 0.995
Q2 (449.5–470.0) 12/65 (18.5) 1.24 (0.64–2.38) 1.24 (0.64–2.38) 0.526 1.02 (0.49–2.11) 0.954 1.63 (0.73–3.66) 0.233
Q3 (470.5–503.5) 21/65 (32.3) 2.61 (1.50–4.53) 2.61 (1.50–4.53) 0.001 2.34 (1.25–4.37) 0.008 2.03 (0.98–4.21) 0.057
Q4 (504.0–727.0) 28/63 (44.4) 4.37 (2.56–7.44) 4.37 (2.56–7.44) <0.001 2.84 (1.55–5.18) 0.001 2.31 (1.09–4.91) 0.030
P for trend test P for trend test <0.001 <0.001 <0.001 0.007