No. of events, n/total (%) Unadjusted Model P Model 1 P Model 2 P
Normal 124/801 (15.5) 1 (Reference) 1 (Reference) 1 (Reference)
No. of abnormal values No. of abnormal values
2 29/138 (21.0) 1.45 (0.92–2.28) 0.106 1.25 (0.76–2.06) 0.385 1.27 (0.72–2.23) 0.414
3 31/97 (32.0) 2.56 (1.61–4.09) <0.001 2.20 (1.30–3.74) 0.003 2.16 (1.21–3.85) 0.009
4 13/22 (59.1) 7.89 (3.30–18.85) <0.001 4.03 (1.51–10.79) 0.006 2.32 (0.66–8.15) 0.188
P for trend test P for trend test <0.001 <0.001 0.011