|
No. of events, n/total (%) |
Unadjusted model |
Unadjusted model |
P |
Model 1† |
P |
Model 2‡ |
P |
Normal |
124/801 (15.5) |
1 (Reference) |
1 (Reference) |
|
1
(Reference) |
|
1 (Reference) |
|
AUC quartile (min–max) |
|
|
|
|
|
|
|
|
Q1 (364.5–449.0) |
12/64 (18.8) |
1.26 (0.65–2.43) |
1.26 (0.65–2.43) |
0.490 |
1.14 (0.56–2.34) |
0.720 |
1.00(0.43–2.29) |
0.995 |
Q2 (449.5–470.0) |
12/65 (18.5) |
1.24 (0.64–2.38) |
1.24 (0.64–2.38) |
0.526 |
1.02 (0.49–2.11) |
0.954 |
1.63 (0.73–3.66) |
0.233 |
Q3 (470.5–503.5) |
21/65 (32.3) |
2.61 (1.50–4.53) |
2.61 (1.50–4.53) |
0.001 |
2.34 (1.25–4.37) |
0.008 |
2.03 (0.98–4.21) |
0.057 |
Q4 (504.0–727.0) |
28/63 (44.4) |
4.37 (2.56–7.44) |
4.37 (2.56–7.44) |
<0.001 |
2.84 (1.55–5.18) |
0.001 |
2.31 (1.09–4.91) |
0.030 |
P for trend test |
P for trend test |
|
<0.001 |
<0.001 |
|
<0.001 |
|
0.007 |