Abstract
Primary pancreatic lymphomas are extremely rare, when present mimics symptoms of adenocarcinoma of the pancreatic head.[1] They account for less than 1% of pancreatic neoplasms.[2] The most common histological subtype is diffuse large B cell lymphoma (DLBCL).[3]Herein, we present a case of a 47 year old female who presented with symptoms of pain abdomen and weight loss. CT (Computerized Tomography) was suggestive of a lesion in the pancreatic head which on histopathology was diagnosed as a primary non Hodgkin’s lymphoma confirmed by immunohistochemistry. She was successfully treated with R-CHOP chemotherapy. This case is presented due to its rarity, and need to recognize NHL (a potentially treatable condition), as a differential to adenocarcinoma for a patient with a pancreatic mass.