Case subjects (n=630) | Case subjects (n=630) | Control subjects (n=1882) | Control subjects (n=1882) | ||
n | % | n | % | p-value | |
Age, years | 0.93 | ||||
65-74 |
176
|
27.9
|
540
|
28.7
|
|
75-79 |
173
|
27.5
|
515
|
27.4
|
|
80+ |
281
|
44.6
|
827
|
43.9
|
|
Mean (SD) |
79.0
|
(6.0)
|
78.8
|
(6.0)
|
0.51
|
Women | 290 | 46.0 | 866 | 46.0 | 0.99 |
Comorbiditities in the past two years | |||||
Diabetes |
246
|
39.1
|
510
|
27.1
|
<.0001
|
Hypertension |
483
|
76.7
|
1255
|
66.7
|
<.0001
|
Hyperlipidemia |
92
|
14.6
|
269
|
14.3
|
0.85
|
CAD |
214
|
34.0
|
556
|
29.5
|
0.04
|
Liver cirrhosis |
61
|
9.7
|
87
|
4.6
|
<.0001
|
COPD |
211
|
33.5
|
406
|
21.6
|
<.0001
|
Renal disease |
79
|
12.5
|
83
|
4.4
|
<.0001
|
CKD |
60
|
9.5
|
59
|
3.1
|
|
ESRD |
19
|
3.0
|
24
|
1.3
|
|
Cancer |
147
|
23.3
|
313
|
16.6
|
.0002
|
Prescribed drugs in the past year | |||||
Antiplatelet |
360
|
57.1
|
855
|
45.4
|
<.0001
|
Aspirin |
252
|
40.0
|
603
|
32.0
|
0.0003
|
Clopidogrel |
49
|
7.8
|
96
|
5.1
|
0.01
|
Thienopyridines |
0
|
0.0
|
0
|
0.0
|
|
OAC |
24
|
3.8
|
41
|
2.2
|
0.03
|
NSAID |
367
|
58.3
|
958
|
50.9
|
0.001
|
SSRI | |||||
Fluoxetine |
304
|
48.3
|
810
|
43.0
|
0.02
|
Citalopram |
150
|
23.8
|
492
|
26.1
|
0.25
|
Paroxetine |
110
|
17.5
|
415
|
22.1
|
0.01
|