CONTRIBUTORS
All authors agree to submit. Cheng Xu and Cheng-Yu Wang wrote the manuscript; Jie Lu and Quanhong Zhou designed the research; Cheng Xu, Fei Gu, Rui Chen and Yang Liu performed the research; Cheng Xu, Cheng-Yu Wang and Qanhong Zhou analyzed the data; Fei Gu and Rui Chen contributed new reagents/analytical tools.
DATA AVAILABILITY STATEMENT
Publicly available datasets were analysed in this study. These data can be found here:http://www.chictr.org.cn(ChiCTR2100045439).