Serelaxin attenuated the CFs proliferation induced by LPS
The CCK-8 assay was used to measure proliferation of the CFs. As shown
in Figure 2, The proliferation of CFs was induced by the LPS
stimulation. Compared with the control group, the OD values were
significantly higher in the LPS group (P < 0.05). However,
compared with the LPS group, CCK-8 assay showed that the OD values in
the serelaxin treated group were decreased markedly. Further analysis
showed that GW9662 could reverse the inhibitory effect of serelaxin and
increase the proliferation of CFs.