Table 2. Effects of eperisone administration on gastric and colonic mucosa
Mice were treated with bleomycin (BLM, 1 mg/kg) or vehicle once only on day 0. The mice were then orally administered 250 mg/kg of eperisone (Epe) once at day 10. After 24 h, the fecal condition (diarrhea or hemorrhagic stool) of the mice was visually examined. Gastric mucosal injury and colonic mucosal injury were analyzed based on the hematotoxin and eosin staining images shown in Figure 5.