Conclusion
We collected evidence suggesting the association between GHD and birthweight discordance in twin pregnancies. Twin gestations complicated with GHD, especially CH and PE, were at significantly higher risk of birthweight discordance. The influence of GHD on intertwin birthweight discordance differed based on chorionicity. GHD had greater effect on the risk of birthweight discordance of DC twins. The findings from the present review suggest that better clinical assessments and evaluations of prognosis, and increased maternal and fetal monitoring in twin pregnancies are justified, which can assist in providing better individualized counseling and optimal pregnancy management for twin gestations complicated by GHD.