Conclusion
We collected evidence suggesting the association between GHD and
birthweight discordance in twin pregnancies.
Twin gestations complicated with
GHD, especially CH and PE, were at significantly higher risk of
birthweight discordance. The influence of GHD on intertwin birthweight
discordance differed based on
chorionicity. GHD had greater
effect on the risk of birthweight discordance of DC twins. The findings
from the present review suggest that better clinical assessments and
evaluations of prognosis, and increased maternal and fetal monitoring in
twin pregnancies are justified,
which can assist in providing better
individualized counseling and optimal pregnancy management for twin
gestations complicated by GHD.