Conclusion
For drinking smokers, both meta-analysis indicated that Varenicline might be a meaningful drug in quitting smoking, while compared with placebo, the remain drugs do not show obvious superiority in smoking cessation. At the same time, we should comprehensively evaluate the safety of these drugs and seek the best dosage. However, based on the limitations of this study, more large-scale and high-quality randomized controlled trials are needed to provide evidence to support the effectiveness and safety of smoking cessation drugs.
Acknowledgements: None.
Conflict of interests: The authors declare that there is no conflict of interests.
Funding: This research is supported by the National Natural Science Foundation of China (Project No. 72074103); the Fundamental Research Funds for the Central Universities:lzujbky-2021-ct06、lzujbky-2021-kb22.
DATE AVAILABILITY STATEMENT: The data that support the findings of this study are available from the corresponding author upon reasonable request.