Data analysis:
We analyzed our data using review manager. Depending on heterogeneity we either used fixed effect model (IQ<75%) or random effect model (IQ>75%)
Subgroup analysis and investigation of heterogeneity
Due to the limited number of studies included we were unable to carry any subgroup analysis. If more trials were available it would have been suitable to analyze according to age (more vs. less than 65 years), gender (Male vs. Female), Follow up time (more vs. less than 12 months), and generation of cryoablation used (1st vs 2nd vs
3rd).