Conclusion
SARS-CoV-2 infection induces immune memory in recovered pediatrics
patients. The T cell reactivity upon stimulation by M, N, S peptide
pools in recovered pediatric patients were similar. There were
differences in the level of SARS-CoV-2 RBD IgG and the magnitude of T
cell responses between younger and older children. Our findings pave the
way for large-scale studies, which could help explain the differences in
clinical findings between children and adults with COVID-19. Our
findings also have important implications for the development of
COVID-19 vaccines targeting younger children.