Contribution to authorship
FVO developed formulation of overarching research goals and aims, verified the overall replication/reproducibility of results/experiments and other research outputs, and acquired financial support for the project leading to this publication. MSGE and FVO were responsible for the research activity planning and execution, including mentorship external to the core team. MSGE, FVO, JBM, NCEM, JCCA, NMC and ECS provided study materials, reagents and contributed to transportation and manage of patient’s samples. DESC, MSGE and AEN contributed to designing of the study. DESC, DAPM and FVO prepared the published work, specifically writing the initial draft. DESC managed activities to scrub data and maintain research data (including software code, where it is necessary for interpreting the data itself) for initial use and later reuse. OYBC and DESC applicated statistical, mathematical, computational, or other formal techniques to analyze or synthesize study data. OYBC contributed to critical review and revision of the published work. All authors contributed to data collection. All of them approved the final version of this manuscript as submitted, and all authors agree to be accountable for all aspects of the work in ensuring that questions related to its accuracy or integrity are appropriately resolved. The corresponding author (FVO) attests that all listed authors meet authorship criteria and that no others meeting the criteria have been omitted.