Introduction
Coccidioidomycosis, known as Valley Fever, is the disease caused by the
inhalation of arthroconidia from the soil-dwelling dimorphic fungi,Coccidioides immitis and Coccidioides posadasii [1].
In the United States, coccidioidomycosis is endemic to the southwestern
part of the country, with most cases located in the San Joaquin Valley
of California and Southern Arizona. The incidence of coccidioidomycosis
is approximately 10,000 cases reported annually [1,2].
Coccidioidomycosis may affect any demographic, but primarily affects
those aged 40-60 years old and has a slight male predominance. Clinical
manifestations range from asymptomatic to disseminated infection
depending on the patient’s immune status.
Cutaneous manifestations in coccidioidomycosis can be classified as
reactive or organism-containing lesions in secondary or primary
cutaneous infection [3]. Sweet syndrome, or acute febrile
neutrophilic dermatosis, is an inflammatory, non-infectious skin
reaction rarely observed as one of the reactive skin manifestations of
coccidioidomycosis. Patients with Sweet syndrome clinically present with
fever, leukocytosis with neutrophilia, and painful erythematous papules,
plaques, pustules, and nodules commonly appearing on the upper limbs,
trunk, head, and neck [4]. Here, we present a case of
coccidioidomycosis associated with Sweet’s syndrome.