A Case Report: Concurrent Treatment Challenges and Outcomes in
Patients with Pulmonary Tuberculosis coexisting Lung Cancer
WANG Na1, SHU Cao 1, WANG
Yajiao2, LIU Ke1.
The First People’s Hospital of Zigong 1. Cancer Center 2. Tuberculosis
Department, Zigong, China.
Corresponding author: SHU Cao,Deputy Chief Physician, Cancer
Center of The First People’s Hospital of Zigong,caoshu129@163.com
Background: Although the coexistence of pulmonary tuberculosis
and lung carcinoma is rare, it poses challenges to treatment strategies.
Understanding the clinical features and treatment outcomes of such
patients is clinically significant. Objective: To
analyze the clinical characteristics and treatment outcomes of
coexisting pulmonary tuberculosis and lung carcinoma, aiming to enhance
clinicians’ comprehensive understanding of this condition.
Methods: A retrospective analysis was conducted on a
patient diagnosed with pulmonary tuberculosis coexisting with lung
carcinoma at the First People’s Hospital of Zigong City. Pathological
and microbiological diagnostics were employed, and the diagnostic and
treatment experiences were summarized. Results: The
patient was an elderly male presenting mainly with cough and hemoptysis.
Diagnosis of pulmonary tuberculosis with concomitant squamous cell
carcinoma of the lung was confirmed through CT, bronchoalveolar lavage
fluid targeted next-generation sequencing (tNGS), and pathological
biopsy. After anti-tuberculosis treatment, concurrent sequential
radiotherapy, and two cycles of chemotherapy, the disease was assessed
as partially relieved. Conclusion: Although the
coexistence of pulmonary tuberculosis and lung carcinoma is rare, the
comprehensive treatment in this case demonstrated favorable outcomes.
Currently, there is no standardized treatment protocol for such
patients, emphasizing the need for further research in this specific
patient population.
Keywords: pulmonary tuberculosis; non-small-cell lung cancer;
radiotherapy; chemotherapy; anti-tuberculosis treatment.