Objective: To study the effect of COVID-19 on pregnancy, neonatal outcomes; and the use of PPE amongst clinicians caring for COVID-19 patients. Design: Prospective cohort study Setting: A large tertiary maternity unit within a university hospital with an average annual >10,000 births. Population: A cohort of 23 pregnant women including singleton and multiple pregnancies tested positive for COVID-19 between February 2020 and April 2020 inclusive. Methods: Analysis of prospectively collected data to assess the effect of COVID-19 on pregnancy, neonatal outcomes; and staff use of PPE. Main outcome Measures Maternal and neonatal morbidity and mortality, and the use of PPE when interacting with COVID-19 patients Results: 23 pregnant women tested positive for COVID-19, delivering 20 babies. 16/23 (70%) were women from Asian background. Nearly fifth of the patients (4/23) developed severe respiratory complications requiring ICU support, one of which was complicated by maternal death (4.3%). (48%) of the patients had pre-existing co-morbidities, with diabetes being the most prevalent (17.4%). (36.4%) of COVID-19 pregnancies had preterm deliveries, (10.5%) respiratory distress, and pre-eclampsia. 16/23 (68%) of patients delivered by C-section. Out of the 20 new-borns, there were no cases of vertical transmission. FFP3 masks were not used by staff in (28.8%) of cases with confirmed COVID-19 infection. Conclusion: COVID-19 is associated with high prevalence of preterm birth, preeclampsia, and caesarean section compared to non-COVID pregnancies. There was no clinical evidence of vertical transmission to the new-borns. PPE use was compliant with WHO recommendations. Funding N/A Keywords COVID-19; maternal morbidity/mortality; neonatal morbidity/mortality; PPE