Objective To assess depression at 2(M2), 6(M6), and 12(M12) postpartum months among women with postpartum haemorrhage (PPH) compared with women with no PPH and, to describe anxiety and post-traumatic stress disorder (PTSD). Design Repeated cross-sectional study within a prospective cohort of women in the immediate postpartum period. Setting Single-centre study at a French level 3 maternity unit. Population Women who gave birth at ≥22 weeks of gestation were eligible. The exposed group comprised the women who had had a primary PPH (≥500 mL in the 24 hours after delivery) and the unexposed group, which did not. Methods 1298 included women (528 with and 770 without PPH) completed self-administered questionnaires. Main Outcome Measures The prevalence of depression and its mean scores, at M2, M6, and M12 and secondary, the prevalence of anxiety and of PTSD and its mean scores, measured at the same times. Results At M2, the prevalence of depression and PTSD was higher among the women with PPH (24.4% vs 18.2%, p=0.03, and 12.8% vs 7.6%, p=0.02). The prevalence of anxiety at inclusion and M2 was higher in the PPH group (18.1% vs 10.3%, p=0.01, and 20.0% vs 13.3%, p=0.01). At M6, and M12, only the mean adjusted PTSD score was higher in the PPH group (7.6, 95%CI, 6.3-9.1 vs 5.8%, 95%CI, 4.9-6.8, p=0.02). Conclusions Professionals must know these high rates and screen for psychological disorders during the long postpartum period. Funding Grant from the Clermont-Ferrand University Hospital AOI2015. Keywords Postpartum haemorrhage; depression; anxiety; post-traumatic stress disorder, psychological disorder
